Autotransplantation of skeletal muscle into myocardium.

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Autotransplantation of skeletal muscle into myocardium.

In a series of 15 studies in dogs, sternocleidomastoid muscle was used to replace deficits created in left ventricular myocardium and sternohyoid muscle was used to replace portions of right myocardial wall. The five right ventricular autotransplants resulted in a 100% surgical success rate, with animals electively killed between 3 and 55 weeks after surgery. In 10 left ventricular studies exci...

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LABORATORY INVESTIGATION CARDIAC SURGERY Autotransplantation of skeletal muscle into myocardium

In a series of 15 studies in dogs, sternocleidomastoid muscle was used to replace deficits created in left ventricular myocardium and stemohyoid muscle was used to replace portions of right myocardial wall. The five right ventricular autotransplants resulted in a 100% surgical success rate, with animals electively killed between 3 and 55 weeks after surgery. In 10 left ventricular studies excis...

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Autotransplantation of parathyroid grafts into the tibialis anterior muscle after parathyroidectomy: a novel autotransplantation site

BACKGROUND Surgical management of renal secondary hyperparathyroidism (sHPT) is varying. Total parathyroidectomy with heterotopic autotransplantation (TPTX + AT) is one of the standard surgical procedures in sHPT, but there is no consensus about the optimal site for graft insertion. At the surgical department of the University Hospital of Heidelberg we prefer the autotransplantation into the ti...

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Noncultured, autologous, skeletal muscle cells can successfully engraft into ovine myocardium.

BACKGROUND There is compelling evidence showing that cellular cardiomyoplasty can improve cardiac function. Considering the potential benefit of using noncultured muscle cells (little time, lower cost, reduced risk of contamination), we investigated the feasibility of grafting cells obtained directly after enzymatic dissociation of skeletal muscle biopsies into ovine myocardium. We hypothesized...

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Myogenic endothelial cells purified from human skeletal muscle improve cardiac function after transplantation into infarcted myocardium.

OBJECTIVES The aim of this study was to evaluate the therapeutic potential of human skeletal muscle-derived myoendothelial cells for myocardial infarct repair. BACKGROUND We have recently identified and purified a novel population of myoendothelial cells from human skeletal muscle. These cells coexpress myogenic and endothelial cell markers and produce robust muscle regeneration when injected...

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ژورنال

عنوان ژورنال: Circulation

سال: 1985

ISSN: 0009-7322,1524-4539

DOI: 10.1161/01.cir.71.2.341